https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36968 2 [IQR 7–21]) compared to benign thyroid (6 nerves/cm² [IQR: 3–10]) (p = 0.001). In contrast, no increase in nerve density was observed in FTC. In multivariate analysis, nerve density correlated positively with extrathyroidal invasion (p < 0.001), and inversely with tumour size (p < 0.001). The majority of nerves were adrenergic, although cholinergic and peptidergic innervation was detected. Perineural invasion was present in 35% of PTC, and was independently associated with extrathyroidal invasion (p = 0.008). This is the first report of infiltration of nerves into the tumour microenvironment of thyroid cancer and its association with tumour aggressiveness. The role of nerves in thyroid cancer pathogenesis should be further investigated.]]> Wed 24 May 2023 12:56:43 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37964 Wed 14 Jul 2021 08:29:30 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20584 Sat 24 Mar 2018 07:55:36 AEDT ]]>